| Difficult Run to Durmersheim | 4,088.18 mi (6,579.30 km) |
| Difficult Run to Dusseldorf | 3,962.65 mi (6,377.28 km) |
| Difficult Run to Eberbach | 4,101.31 mi (6,600.43 km) |
| Difficult Run to Ebersbach an der Fils | 4,145.97 mi (6,672.29 km) |
| Difficult Run to Ebersberg | 4,265.61 mi (6,864.83 km) |
| Difficult Run to Eberswalde | 4,187.78 mi (6,739.58 km) |
| Difficult Run to Eching | 4,244.37 mi (6,830.65 km) |
| Difficult Run to Eckernforde | 3,991.62 mi (6,423.90 km) |
| Difficult Run to Edemissen | 4,066.94 mi (6,545.11 km) |
| Difficult Run to Edewecht | 3,958.38 mi (6,370.39 km) |
| Difficult Run to Edingen-Neckarhausen | 4,086.73 mi (6,576.95 km) |
| Difficult Run to Efringen-Kirchen | 4,096.83 mi (6,593.21 km) |
| Difficult Run to Egelsbach | 4,073.70 mi (6,555.99 km) |
| Difficult Run to Eggenfelden | 4,287.55 mi (6,900.15 km) |
| Difficult Run to Eggenstein-Leopoldshafen | 4,088.79 mi (6,580.27 km) |
