| Difficult Run to Ennepetal | 3,983.13 mi (6,410.22 km) |
| Difficult Run to Ennigerloh | 3,995.13 mi (6,429.53 km) |
| Difficult Run to Eppelborn | 4,021.17 mi (6,471.45 km) |
| Difficult Run to Eppelheim | 4,089.08 mi (6,580.75 km) |
| Difficult Run to Eppingen | 4,108.54 mi (6,612.06 km) |
| Difficult Run to Eppstein | 4,058.20 mi (6,531.04 km) |
| Difficult Run to Erbach | 4,172.77 mi (6,715.43 km) |
| Difficult Run to Erbach | 4,096.06 mi (6,591.98 km) |
| Difficult Run to Erding | 4,256.43 mi (6,850.07 km) |
| Difficult Run to Erftstadt | 3,973.37 mi (6,394.51 km) |
| Difficult Run to Erfurt | 4,137.51 mi (6,658.68 km) |
| Difficult Run to Ergolding | 4,257.58 mi (6,851.91 km) |
| Difficult Run to Erkelenz | 3,948.11 mi (6,353.87 km) |
| Difficult Run to Erkner | 4,197.65 mi (6,755.47 km) |
| Difficult Run to Erkrath | 3,968.14 mi (6,386.10 km) |
