| Difficult Run to Erlangen | 4,179.69 mi (6,726.57 km) |
| Difficult Run to Erlenbach am Main | 4,098.60 mi (6,596.05 km) |
| Difficult Run to Erlensee | 4,079.62 mi (6,565.51 km) |
| Difficult Run to Erwitte | 4,013.96 mi (6,459.84 km) |
| Difficult Run to Eschborn | 4,064.73 mi (6,541.56 km) |
| Difficult Run to Eschwege | 4,093.02 mi (6,587.08 km) |
| Difficult Run to Eschweiler | 3,953.98 mi (6,363.31 km) |
| Difficult Run to Eslohe | 4,017.03 mi (6,464.79 km) |
| Difficult Run to Espelkamp | 4,003.77 mi (6,443.44 km) |
| Difficult Run to Essen | 3,965.86 mi (6,382.43 km) |
| Difficult Run to Essenbach | 4,258.52 mi (6,853.43 km) |
| Difficult Run to Esslingen | 4,136.93 mi (6,657.75 km) |
| Difficult Run to Ettenheim | 4,089.23 mi (6,580.98 km) |
| Difficult Run to Ettlingen | 4,093.38 mi (6,587.66 km) |
| Difficult Run to Euskirchen | 3,978.69 mi (6,403.08 km) |
