| Difficult Run to Stephanskirchen | 4,282.03 mi (6,891.27 km) |
| Difficult Run to Stockach | 4,151.26 mi (6,680.81 km) |
| Difficult Run to Stockelsdorf | 4,038.10 mi (6,498.69 km) |
| Difficult Run to Stolberg | 3,953.32 mi (6,362.26 km) |
| Difficult Run to Stollberg | 4,214.11 mi (6,781.95 km) |
| Difficult Run to Straelen | 3,936.29 mi (6,334.84 km) |
| Difficult Run to Stralsund | 4,115.20 mi (6,622.77 km) |
| Difficult Run to Straubing | 4,264.01 mi (6,862.26 km) |
| Difficult Run to Strausberg | 4,197.44 mi (6,755.13 km) |
| Difficult Run to Stuhr | 3,990.64 mi (6,422.32 km) |
| Difficult Run to Stuttgart | 4,130.00 mi (6,646.59 km) |
| Difficult Run to Sudlohn | 3,946.78 mi (6,351.73 km) |
| Difficult Run to Suhl | 4,135.41 mi (6,655.30 km) |
| Difficult Run to Sulingen | 4,002.19 mi (6,440.90 km) |
| Difficult Run to Sulz am Neckar | 4,119.98 mi (6,630.46 km) |
