| Difficult Run to Acqui Terme | 4,227.79 mi (6,803.97 km) |
| Difficult Run to Acri | 4,758.91 mi (7,658.73 km) |
| Difficult Run to Adelfia | 4,722.94 mi (7,600.84 km) |
| Difficult Run to Adrano | 4,759.23 mi (7,659.24 km) |
| Difficult Run to Adria | 4,369.59 mi (7,032.18 km) |
| Difficult Run to Afragola | 4,614.19 mi (7,425.82 km) |
| Difficult Run to Agliana | 4,363.40 mi (7,022.22 km) |
| Difficult Run to Agrate Brianza | 4,236.74 mi (6,818.38 km) |
| Difficult Run to Agrigento | 4,715.24 mi (7,588.44 km) |
| Difficult Run to Agropoli | 4,664.69 mi (7,507.09 km) |
| Difficult Run to Ala | 4,301.61 mi (6,922.78 km) |
| Difficult Run to Alassio | 4,236.33 mi (6,817.71 km) |
| Difficult Run to Alatri | 4,541.77 mi (7,309.26 km) |
| Difficult Run to Alba | 4,208.07 mi (6,772.23 km) |
| Difficult Run to Albano Laziale | 4,511.71 mi (7,260.89 km) |
