| Difficult Run to Amelia | 4,471.78 mi (7,196.64 km) |
| Difficult Run to Anagni | 4,533.07 mi (7,295.27 km) |
| Difficult Run to Ancona | 4,481.92 mi (7,212.95 km) |
| Difficult Run to Andria | 4,690.06 mi (7,547.92 km) |
| Difficult Run to Angri | 4,632.00 mi (7,454.49 km) |
| Difficult Run to Anguillara Sabazia | 4,481.64 mi (7,212.50 km) |
| Difficult Run to Anzio | 4,520.22 mi (7,274.59 km) |
| Difficult Run to Anzola dell'Emilia | 4,350.02 mi (7,000.68 km) |
| Difficult Run to Aosta | 4,144.61 mi (6,670.10 km) |
| Difficult Run to Apricena | 4,631.78 mi (7,454.13 km) |
| Difficult Run to Aprilia | 4,516.32 mi (7,268.31 km) |
| Difficult Run to Aradeo | 4,811.50 mi (7,743.37 km) |
| Difficult Run to Aragona | 4,713.63 mi (7,585.86 km) |
| Difficult Run to Arco | 4,291.19 mi (6,906.00 km) |
| Difficult Run to Arcola | 4,308.33 mi (6,933.59 km) |
