| Difficult Run to Carmignano | 4,366.95 mi (7,027.92 km) |
| Difficult Run to Carovigno | 4,769.23 mi (7,675.34 km) |
| Difficult Run to Carpenedolo | 4,290.11 mi (6,904.26 km) |
| Difficult Run to Carpi | 4,328.69 mi (6,966.35 km) |
| Difficult Run to Carrara | 4,318.28 mi (6,949.60 km) |
| Difficult Run to Carugate | 4,237.10 mi (6,818.95 km) |
| Difficult Run to Casal di Principe | 4,602.41 mi (7,406.86 km) |
| Difficult Run to Casale Monferrato | 4,212.71 mi (6,779.70 km) |
| Difficult Run to Casale sul Sile | 4,362.98 mi (7,021.54 km) |
| Difficult Run to Casalecchio di Reno | 4,355.94 mi (7,010.21 km) |
| Difficult Run to Casalgrande | 4,328.91 mi (6,966.70 km) |
| Difficult Run to Casalmaggiore | 4,301.85 mi (6,923.15 km) |
| Difficult Run to Casalnuovo di Napoli | 4,615.66 mi (7,428.19 km) |
| Difficult Run to Casalpusterlengo | 4,262.71 mi (6,860.16 km) |
| Difficult Run to Casaluce | 4,605.97 mi (7,412.59 km) |
