| Difficult Run to Castrovillari | 4,738.69 mi (7,626.19 km) |
| Difficult Run to Catania | 4,777.32 mi (7,688.36 km) |
| Difficult Run to Catanzaro | 4,791.61 mi (7,711.35 km) |
| Difficult Run to Cattolica | 4,435.99 mi (7,139.03 km) |
| Difficult Run to Cava de' Tirreni | 4,639.13 mi (7,465.96 km) |
| Difficult Run to Cavallino | 4,807.28 mi (7,736.56 km) |
| Difficult Run to Cavarzere | 4,367.99 mi (7,029.60 km) |
| Difficult Run to Cave | 4,520.49 mi (7,275.02 km) |
| Difficult Run to Cavriago | 4,316.41 mi (6,946.58 km) |
| Difficult Run to Cavriglia | 4,397.46 mi (7,077.02 km) |
| Difficult Run to Cazzago San Martino | 4,265.69 mi (6,864.96 km) |
| Difficult Run to Ceccano | 4,547.10 mi (7,317.85 km) |
| Difficult Run to Cecina | 4,362.06 mi (7,020.06 km) |
| Difficult Run to Cefalu | 4,708.08 mi (7,576.93 km) |
| Difficult Run to Ceglie Messapico | 4,763.90 mi (7,666.76 km) |
