| Difficult Run to Cividale del Friuli | 4,392.08 mi (7,068.37 km) |
| Difficult Run to Civita Castellana | 4,480.43 mi (7,210.56 km) |
| Difficult Run to Civitanova Marche | 4,502.47 mi (7,246.03 km) |
| Difficult Run to Civitavecchia | 4,460.46 mi (7,178.41 km) |
| Difficult Run to Civitella in Val di Chiana | 4,411.05 mi (7,098.89 km) |
| Difficult Run to Clusone | 4,252.69 mi (6,844.05 km) |
| Difficult Run to Coccaglio | 4,264.26 mi (6,862.66 km) |
| Difficult Run to Codigoro | 4,379.79 mi (7,048.59 km) |
| Difficult Run to Codogno | 4,265.65 mi (6,864.90 km) |
| Difficult Run to Codroipo | 4,377.82 mi (7,045.42 km) |
| Difficult Run to Cogoleto | 4,244.75 mi (6,831.27 km) |
| Difficult Run to Colle di Val d'Elsa | 4,386.20 mi (7,058.90 km) |
| Difficult Run to Colle Salvetti | 4,351.03 mi (7,002.31 km) |
| Difficult Run to Collecchio | 4,301.11 mi (6,921.96 km) |
| Difficult Run to Colleferro | 4,527.15 mi (7,285.74 km) |
