| Difficult Run to Collegno | 4,176.08 mi (6,720.75 km) |
| Difficult Run to Cologno al Serio | 4,251.72 mi (6,842.48 km) |
| Difficult Run to Cologno Monzese | 4,235.43 mi (6,816.26 km) |
| Difficult Run to Colorno | 4,302.23 mi (6,923.77 km) |
| Difficult Run to Comacchio | 4,387.17 mi (7,060.47 km) |
| Difficult Run to Comiso | 4,775.94 mi (7,686.13 km) |
| Difficult Run to Como | 4,218.20 mi (6,788.53 km) |
| Difficult Run to Concordia Sagittaria | 4,379.06 mi (7,047.42 km) |
| Difficult Run to Concorezzo | 4,235.93 mi (6,817.08 km) |
| Difficult Run to Conegliano | 4,351.80 mi (7,003.55 km) |
| Difficult Run to Conselice | 4,378.44 mi (7,046.41 km) |
| Difficult Run to Conselve | 4,355.61 mi (7,009.67 km) |
| Difficult Run to Conversano | 4,735.09 mi (7,620.39 km) |
| Difficult Run to Copertino | 4,802.68 mi (7,729.17 km) |
| Difficult Run to Copparo | 4,365.44 mi (7,025.49 km) |
