| Difficult Run to Forli | 4,397.41 mi (7,076.96 km) |
| Difficult Run to Forlimpopoli | 4,402.71 mi (7,085.48 km) |
| Difficult Run to Formello | 4,487.51 mi (7,221.95 km) |
| Difficult Run to Formia | 4,570.46 mi (7,355.45 km) |
| Difficult Run to Formigine | 4,336.72 mi (6,979.28 km) |
| Difficult Run to Fossano | 4,199.73 mi (6,758.81 km) |
| Difficult Run to Fossombrone | 4,448.86 mi (7,159.76 km) |
| Difficult Run to Francavilla al Mare | 4,558.70 mi (7,336.52 km) |
| Difficult Run to Francavilla Fontana | 4,772.02 mi (7,679.83 km) |
| Difficult Run to Francofonte | 4,778.08 mi (7,689.58 km) |
| Difficult Run to Frascati | 4,509.47 mi (7,257.28 km) |
| Difficult Run to Frattamaggiore | 4,612.10 mi (7,422.46 km) |
| Difficult Run to Frattaminore | 4,610.75 mi (7,420.29 km) |
| Difficult Run to Frosinone | 4,545.43 mi (7,315.17 km) |
| Difficult Run to Fucecchio | 4,360.34 mi (7,017.30 km) |
