| Difficult Run to Manerbio | 4,277.28 mi (6,883.62 km) |
| Difficult Run to Manfredonia | 4,657.76 mi (7,495.93 km) |
| Difficult Run to Maniago | 4,359.93 mi (7,016.64 km) |
| Difficult Run to Mantova | 4,312.33 mi (6,940.03 km) |
| Difficult Run to Maranello | 4,336.32 mi (6,978.64 km) |
| Difficult Run to Marano di Napoli | 4,608.90 mi (7,417.31 km) |
| Difficult Run to Marano Vicentino | 4,321.61 mi (6,954.97 km) |
| Difficult Run to Marcianise | 4,609.16 mi (7,417.73 km) |
| Difficult Run to Marcon | 4,363.09 mi (7,021.72 km) |
| Difficult Run to Mareno di Piave | 4,355.64 mi (7,009.73 km) |
| Difficult Run to Margherita di Savoia | 4,677.88 mi (7,528.33 km) |
| Difficult Run to Mariano Comense | 4,225.87 mi (6,800.88 km) |
| Difficult Run to Marigliano | 4,619.46 mi (7,434.31 km) |
| Difficult Run to Marino | 4,510.51 mi (7,258.97 km) |
| Difficult Run to Marostica | 4,329.48 mi (6,967.63 km) |
