| Difficult Run to Marsala | 4,644.31 mi (7,474.29 km) |
| Difficult Run to Marsciano | 4,455.27 mi (7,170.07 km) |
| Difficult Run to Martano | 4,816.18 mi (7,750.89 km) |
| Difficult Run to Martellago | 4,357.36 mi (7,012.49 km) |
| Difficult Run to Martina Franca | 4,754.72 mi (7,651.98 km) |
| Difficult Run to Martinengo | 4,255.02 mi (6,847.79 km) |
| Difficult Run to Martinsicuro | 4,525.27 mi (7,282.72 km) |
| Difficult Run to Mascali | 4,772.74 mi (7,680.98 km) |
| Difficult Run to Mascalucia | 4,772.93 mi (7,681.29 km) |
| Difficult Run to Masera di Padova | 4,352.80 mi (7,005.15 km) |
| Difficult Run to Maserada sul Piave | 4,357.22 mi (7,012.27 km) |
| Difficult Run to Massa | 4,321.26 mi (6,954.39 km) |
| Difficult Run to Massa Lombarda | 4,379.99 mi (7,048.92 km) |
| Difficult Run to Massafra | 4,749.74 mi (7,643.97 km) |
| Difficult Run to Massalubrense | 4,626.72 mi (7,445.98 km) |
