| Difficult Run to Minervino Murge | 4,684.99 mi (7,539.77 km) |
| Difficult Run to Minturno | 4,576.35 mi (7,364.92 km) |
| Difficult Run to Mira | 4,360.00 mi (7,016.75 km) |
| Difficult Run to Mirandola | 4,333.05 mi (6,973.37 km) |
| Difficult Run to Mirano | 4,356.50 mi (7,011.12 km) |
| Difficult Run to Misano Adriatico | 4,434.56 mi (7,136.73 km) |
| Difficult Run to Misilmeri | 4,682.19 mi (7,535.26 km) |
| Difficult Run to Missaglia | 4,232.29 mi (6,811.21 km) |
| Difficult Run to Misterbianco | 4,772.82 mi (7,681.11 km) |
| Difficult Run to Modena | 4,335.10 mi (6,976.67 km) |
| Difficult Run to Modica | 4,786.53 mi (7,703.18 km) |
| Difficult Run to Modugno | 4,716.15 mi (7,589.90 km) |
| Difficult Run to Mogliano Veneto | 4,360.18 mi (7,017.03 km) |
| Difficult Run to Molfetta | 4,703.75 mi (7,569.95 km) |
| Difficult Run to Molinella | 4,367.90 mi (7,029.46 km) |
