| Difficult Run to Montevarchi | 4,400.82 mi (7,082.44 km) |
| Difficult Run to Monticello Conte Otto | 4,331.29 mi (6,970.54 km) |
| Difficult Run to Montichiari | 4,286.71 mi (6,898.79 km) |
| Difficult Run to Montignoso | 4,323.26 mi (6,957.62 km) |
| Difficult Run to Montopoli in Val d'Arno | 4,360.42 mi (7,017.41 km) |
| Difficult Run to Monza | 4,233.46 mi (6,813.10 km) |
| Difficult Run to Morbegno | 4,228.38 mi (6,804.92 km) |
| Difficult Run to Mori | 4,297.61 mi (6,916.34 km) |
| Difficult Run to Morlupo | 4,489.99 mi (7,225.94 km) |
| Difficult Run to Morrovalle | 4,495.41 mi (7,234.67 km) |
| Difficult Run to Mortara | 4,221.62 mi (6,794.04 km) |
| Difficult Run to Mosciano Sant'Angelo | 4,528.60 mi (7,288.08 km) |
| Difficult Run to Motta di Livenza | 4,368.49 mi (7,030.40 km) |
| Difficult Run to Motta Sant'Anastasia | 4,771.68 mi (7,679.28 km) |
| Difficult Run to Mottola | 4,744.19 mi (7,635.03 km) |
