| Difficult Run to Sant'Arcangelo di Romagna | 4,420.31 mi (7,113.81 km) |
| Difficult Run to Sant'Arpino | 4,609.70 mi (7,418.60 km) |
| Difficult Run to Sant'Egidio alla Vibrata | 4,518.40 mi (7,271.66 km) |
| Difficult Run to Sant'Elpidio a Mare | 4,502.95 mi (7,246.79 km) |
| Difficult Run to Sant'Ilario d'Enza | 4,310.61 mi (6,937.25 km) |
| Difficult Run to Santa Croce Camerina | 4,777.14 mi (7,688.07 km) |
| Difficult Run to Santa Croce sull' Arno | 4,359.60 mi (7,016.10 km) |
| Difficult Run to Santa Flavia | 4,684.13 mi (7,538.38 km) |
| Difficult Run to Santa Lucia di Piave | 4,352.45 mi (7,004.59 km) |
| Difficult Run to Santa Maria a Monte | 4,356.39 mi (7,010.93 km) |
| Difficult Run to Santa Maria a Vico | 4,617.25 mi (7,430.75 km) |
| Difficult Run to Santa Maria Capua Vetere | 4,605.12 mi (7,411.23 km) |
| Difficult Run to Santa Maria di Sala | 4,353.51 mi (7,006.30 km) |
| Difficult Run to Santa Marinella | 4,465.01 mi (7,185.73 km) |
| Difficult Run to Santa Teresa di Riva | 4,772.84 mi (7,681.15 km) |
