| Difficult Run to Staro Nagoricane | 4,887.54 mi (7,865.74 km) |
| Difficult Run to Stip | 4,921.33 mi (7,920.11 km) |
| Difficult Run to Struga | 4,880.02 mi (7,853.63 km) |
| Difficult Run to Strumica | 4,952.33 mi (7,970.00 km) |
| Difficult Run to Studenicani | 4,886.43 mi (7,863.96 km) |
| Difficult Run to Sveti Nikole | 4,905.71 mi (7,894.98 km) |
| Difficult Run to Tearce | 4,859.92 mi (7,821.28 km) |
| Difficult Run to Tetovo | 4,859.21 mi (7,820.15 km) |
| Difficult Run to Valandovo | 4,953.81 mi (7,972.39 km) |
| Difficult Run to Vasilevo | 4,950.71 mi (7,967.40 km) |
| Difficult Run to Veles | 4,904.74 mi (7,893.42 km) |
| Difficult Run to Vevcani | 4,873.87 mi (7,843.74 km) |
| Difficult Run to Vinica | 4,928.63 mi (7,931.86 km) |
| Difficult Run to Vrapciste | 4,862.61 mi (7,825.61 km) |
| Difficult Run to Zelenikovo | 4,889.96 mi (7,869.63 km) |
