| Difficult Run to Tubbergen | 3,931.40 mi (6,326.97 km) |
| Difficult Run to Tynaarlo | 3,905.82 mi (6,285.81 km) |
| Difficult Run to Ubbergen | 3,912.29 mi (6,296.22 km) |
| Difficult Run to Uden | 3,905.20 mi (6,284.81 km) |
| Difficult Run to Uitgeest | 3,847.19 mi (6,191.46 km) |
| Difficult Run to Uithoorn | 3,859.27 mi (6,210.90 km) |
| Difficult Run to Ulft | 3,929.04 mi (6,323.19 km) |
| Difficult Run to Urk | 3,878.38 mi (6,241.66 km) |
| Difficult Run to Utrecht | 3,874.24 mi (6,234.99 km) |
| Difficult Run to Vaals | 3,944.61 mi (6,348.24 km) |
| Difficult Run to Valkenswaard | 3,907.07 mi (6,287.81 km) |
| Difficult Run to Veendam | 3,916.93 mi (6,303.68 km) |
| Difficult Run to Veenendaal | 3,893.05 mi (6,265.26 km) |
| Difficult Run to Veenoord | 3,897.03 mi (6,271.66 km) |
| Difficult Run to Veghel | 3,903.42 mi (6,281.94 km) |
