| Difficult Run to Sierpc | 4,399.72 mi (7,080.66 km) |
| Difficult Run to Skarzysko-Kamienna | 4,508.49 mi (7,255.72 km) |
| Difficult Run to Skawina | 4,509.48 mi (7,257.30 km) |
| Difficult Run to Skierniewice | 4,449.66 mi (7,161.04 km) |
| Difficult Run to Skoczow | 4,476.41 mi (7,204.08 km) |
| Difficult Run to Skwierzyna | 4,257.15 mi (6,851.22 km) |
| Difficult Run to Slawno | 4,243.01 mi (6,828.46 km) |
| Difficult Run to Slubice | 4,230.40 mi (6,808.17 km) |
| Difficult Run to Slupca | 4,354.48 mi (7,007.86 km) |
| Difficult Run to Slupsk | 4,252.11 mi (6,843.11 km) |
| Difficult Run to Sochaczew | 4,443.16 mi (7,150.58 km) |
| Difficult Run to Sokolka | 4,516.28 mi (7,268.24 km) |
| Difficult Run to Sokolow Podlaski | 4,509.55 mi (7,257.41 km) |
| Difficult Run to Solec Kujawski | 4,341.17 mi (6,986.43 km) |
| Difficult Run to Sopot | 4,306.87 mi (6,931.24 km) |
