| Difficult Run to Mangualde | 3,597.18 mi (5,789.10 km) |
| Difficult Run to Marco de Canavezes | 3,563.32 mi (5,734.61 km) |
| Difficult Run to Marinha Grande | 3,562.50 mi (5,733.29 km) |
| Difficult Run to Massama | 3,572.24 mi (5,748.97 km) |
| Difficult Run to Matosinhos | 3,536.74 mi (5,691.83 km) |
| Difficult Run to Mealhada | 3,569.48 mi (5,744.53 km) |
| Difficult Run to Melgaco | 3,534.18 mi (5,687.71 km) |
| Difficult Run to Melres | 3,554.23 mi (5,719.97 km) |
| Difficult Run to Mira | 3,554.38 mi (5,720.21 km) |
| Difficult Run to Miranda do Corvo | 3,582.62 mi (5,765.67 km) |
| Difficult Run to Mirandela | 3,602.16 mi (5,797.12 km) |
| Difficult Run to Mogadouro | 3,628.44 mi (5,839.41 km) |
| Difficult Run to Moimenta da Beira | 3,594.49 mi (5,784.78 km) |
| Difficult Run to Moita | 3,589.60 mi (5,776.90 km) |
| Difficult Run to Moncao | 3,525.04 mi (5,673.01 km) |
