| Difficult Run to Santarem | 3,588.44 mi (5,775.04 km) |
| Difficult Run to Santiago do Cacem | 3,621.16 mi (5,827.70 km) |
| Difficult Run to Santo Andre | 3,617.74 mi (5,822.19 km) |
| Difficult Run to Santo Tirso | 3,544.21 mi (5,703.85 km) |
| Difficult Run to Sao Bras de Alportel | 3,686.55 mi (5,932.93 km) |
| Difficult Run to Sao Felix da Marinha | 3,544.27 mi (5,703.95 km) |
| Difficult Run to Sao Joao da Madeira | 3,554.27 mi (5,720.04 km) |
| Difficult Run to Sao Joao de Ver | 3,549.80 mi (5,712.85 km) |
| Difficult Run to Sao Mamede de Infesta | 3,541.15 mi (5,698.93 km) |
| Difficult Run to Sao Pedro do Sul | 3,578.55 mi (5,759.11 km) |
| Difficult Run to Satao | 3,595.14 mi (5,785.82 km) |
| Difficult Run to Seia | 3,604.84 mi (5,801.42 km) |
| Difficult Run to Senhora da Hora | 3,539.04 mi (5,695.54 km) |
| Difficult Run to Serpa | 3,677.94 mi (5,919.08 km) |
| Difficult Run to Serta | 3,602.01 mi (5,796.87 km) |
