| Difficult Run to Cehegin | 3,958.87 mi (6,371.19 km) |
| Difficult Run to Cervello | 4,036.88 mi (6,496.72 km) |
| Difficult Run to Cervera | 3,996.74 mi (6,432.12 km) |
| Difficult Run to Ceuti | 3,984.92 mi (6,413.11 km) |
| Difficult Run to Cheste | 3,970.32 mi (6,389.62 km) |
| Difficult Run to Chiclana de la Frontera | 3,794.91 mi (6,107.32 km) |
| Difficult Run to Chipiona | 3,771.27 mi (6,069.27 km) |
| Difficult Run to Chiva | 3,968.88 mi (6,387.30 km) |
| Difficult Run to Churriana de la Vega | 3,896.98 mi (6,271.58 km) |
| Difficult Run to Ciempozuelos | 3,809.49 mi (6,130.78 km) |
| Difficult Run to Cieza | 3,972.84 mi (6,393.67 km) |
| Difficult Run to Cisterniga | 3,718.04 mi (5,983.61 km) |
| Difficult Run to Ciudad de Melilla | 3,990.34 mi (6,421.83 km) |
| Difficult Run to Ciudad Real | 3,829.05 mi (6,162.26 km) |
| Difficult Run to Ciudad-Rodrigo | 3,656.54 mi (5,884.63 km) |
