| Difficult Run to Cuenca | 3,882.61 mi (6,248.46 km) |
| Difficult Run to Cuevas del Almanzora | 3,980.11 mi (6,405.36 km) |
| Difficult Run to Cullera | 4,000.72 mi (6,438.53 km) |
| Difficult Run to Culleredo | 3,499.92 mi (5,632.57 km) |
| Difficult Run to Cunit | 4,027.80 mi (6,482.12 km) |
| Difficult Run to Daganzo de Arriba | 3,806.28 mi (6,125.61 km) |
| Difficult Run to Daimiel | 3,840.71 mi (6,181.02 km) |
| Difficult Run to Don Benito | 3,734.93 mi (6,010.79 km) |
| Difficult Run to Donostia | 3,798.69 mi (6,113.39 km) |
| Difficult Run to Dos Hermanas | 3,780.41 mi (6,083.98 km) |
| Difficult Run to Durango | 3,772.67 mi (6,071.52 km) |
| Difficult Run to Ecija | 3,814.58 mi (6,138.98 km) |
| Difficult Run to Ejea de los Caballeros | 3,870.96 mi (6,229.70 km) |
| Difficult Run to El Alamo | 3,789.37 mi (6,098.40 km) |
| Difficult Run to El Arahal | 3,799.39 mi (6,114.53 km) |
