| Difficult Run to Redondela | 3,513.34 mi (5,654.17 km) |
| Difficult Run to Reinosa | 3,706.88 mi (5,965.65 km) |
| Difficult Run to Requena | 3,950.13 mi (6,357.11 km) |
| Difficult Run to Reus | 4,004.52 mi (6,444.66 km) |
| Difficult Run to Rianxo | 3,494.89 mi (5,624.49 km) |
| Difficult Run to Ribadeo | 3,557.54 mi (5,725.30 km) |
| Difficult Run to Rincon de la Victoria | 3,878.87 mi (6,242.44 km) |
| Difficult Run to Ripoll | 4,023.22 mi (6,474.75 km) |
| Difficult Run to Ripollet | 4,043.03 mi (6,506.63 km) |
| Difficult Run to Rojales | 4,011.26 mi (6,455.50 km) |
| Difficult Run to Ronda | 3,834.43 mi (6,170.91 km) |
| Difficult Run to Roquetas de Mar | 3,960.02 mi (6,373.04 km) |
| Difficult Run to Rosas | 4,066.60 mi (6,544.56 km) |
| Difficult Run to Rubi | 4,037.34 mi (6,497.47 km) |
| Difficult Run to Rute | 3,856.50 mi (6,206.44 km) |
