| Difficult Run to Uhersky Brod | 4,460.07 mi (7,177.79 km) |
| Difficult Run to Unicov | 4,413.53 mi (7,102.89 km) |
| Difficult Run to Usti nad Labem | 4,264.74 mi (6,863.44 km) |
| Difficult Run to Usti nad Orlici | 4,378.45 mi (7,046.43 km) |
| Difficult Run to Valasske Mezirici | 4,456.79 mi (7,172.51 km) |
| Difficult Run to Varnsdorf | 4,278.74 mi (6,885.97 km) |
| Difficult Run to Velke Mezirici | 4,384.82 mi (7,056.68 km) |
| Difficult Run to Veseli nad Moravou | 4,452.05 mi (7,164.89 km) |
| Difficult Run to Vlasim | 4,329.40 mi (6,967.50 km) |
| Difficult Run to Vrchlabi | 4,326.18 mi (6,962.32 km) |
| Difficult Run to Vsetin | 4,462.48 mi (7,181.66 km) |
| Difficult Run to Vyskov | 4,425.97 mi (7,122.92 km) |
| Difficult Run to Vysoke Myto | 4,370.19 mi (7,033.14 km) |
| Difficult Run to Zabreh | 4,400.05 mi (7,081.20 km) |
| Difficult Run to Zatec | 4,256.17 mi (6,849.64 km) |
