| Difficult Run to Egg | 4,154.75 mi (6,686.43 km) |
| Difficult Run to Einsiedeln | 4,162.26 mi (6,698.51 km) |
| Difficult Run to Embrach | 4,144.28 mi (6,669.57 km) |
| Difficult Run to Emmen | 4,145.04 mi (6,670.80 km) |
| Difficult Run to Epalinges | 4,091.83 mi (6,585.16 km) |
| Difficult Run to Eschenbach | 4,167.42 mi (6,706.82 km) |
| Difficult Run to Estavayer-le-Lac | 4,090.55 mi (6,583.10 km) |
| Difficult Run to Fallanden | 4,150.48 mi (6,679.56 km) |
| Difficult Run to Flawil | 4,172.78 mi (6,715.45 km) |
| Difficult Run to Frauenfeld | 4,155.88 mi (6,688.24 km) |
| Difficult Run to Freienbach | 4,160.39 mi (6,695.49 km) |
| Difficult Run to Fribourg | 4,104.94 mi (6,606.26 km) |
| Difficult Run to Fully | 4,123.73 mi (6,636.50 km) |
| Difficult Run to Geneva | 4,079.92 mi (6,566.00 km) |
| Difficult Run to Gland | 4,078.70 mi (6,564.04 km) |
