| Difficult Run to Nyon | 4,078.22 mi (6,563.26 km) |
| Difficult Run to Oberriet | 4,190.96 mi (6,744.69 km) |
| Difficult Run to Obersiggenthal | 4,132.38 mi (6,650.42 km) |
| Difficult Run to Oberwil | 4,100.61 mi (6,599.30 km) |
| Difficult Run to Oberwingert | 4,151.42 mi (6,681.07 km) |
| Difficult Run to Oftringen | 4,121.78 mi (6,633.36 km) |
| Difficult Run to Olten | 4,120.07 mi (6,630.61 km) |
| Difficult Run to Onex | 4,078.45 mi (6,563.63 km) |
| Difficult Run to Opfikon | 4,145.52 mi (6,671.57 km) |
| Difficult Run to Ostermundigen | 4,114.68 mi (6,621.93 km) |
| Difficult Run to Payerne | 4,095.21 mi (6,590.60 km) |
| Difficult Run to Pfaffikon | 4,156.64 mi (6,689.47 km) |
| Difficult Run to Plan-les-Ouates | 4,079.67 mi (6,565.59 km) |
| Difficult Run to Pratteln | 4,106.63 mi (6,608.98 km) |
| Difficult Run to Prilly | 4,089.47 mi (6,581.37 km) |
