| Difficult Run to Sereflikochisar | 5,506.28 mi (8,861.50 km) |
| Difficult Run to Serik | 5,500.63 mi (8,852.41 km) |
| Difficult Run to Serinhisar | 5,394.49 mi (8,681.59 km) |
| Difficult Run to Serinyol | 5,734.17 mi (9,228.26 km) |
| Difficult Run to Seydisehir | 5,508.60 mi (8,865.24 km) |
| Difficult Run to Seyhan | 5,670.01 mi (9,125.00 km) |
| Difficult Run to Seyitgazi | 5,369.20 mi (8,640.90 km) |
| Difficult Run to Siirt | 5,879.02 mi (9,461.37 km) |
| Difficult Run to Sile | 5,248.39 mi (8,446.46 km) |
| Difficult Run to Silifke | 5,642.14 mi (9,080.15 km) |
| Difficult Run to Silivri | 5,198.11 mi (8,365.56 km) |
| Difficult Run to Silopi | 5,932.83 mi (9,547.96 km) |
| Difficult Run to Simav | 5,315.68 mi (8,554.76 km) |
| Difficult Run to Sinanpasa | 5,382.51 mi (8,662.31 km) |
| Difficult Run to Sindirgi | 5,275.46 mi (8,490.02 km) |
