| Difficult Run to Sinop | 5,424.45 mi (8,729.82 km) |
| Difficult Run to Siran | 5,661.43 mi (9,111.20 km) |
| Difficult Run to Sirnak | 5,918.61 mi (9,525.08 km) |
| Difficult Run to Sirvan | 5,875.05 mi (9,454.98 km) |
| Difficult Run to Sivas | 5,603.39 mi (9,017.79 km) |
| Difficult Run to Sivasli | 5,371.23 mi (8,644.16 km) |
| Difficult Run to Siverek | 5,788.71 mi (9,316.02 km) |
| Difficult Run to Sivrice | 5,754.14 mi (9,260.39 km) |
| Difficult Run to Sivrihisar | 5,402.99 mi (8,695.27 km) |
| Difficult Run to Sogut | 5,322.77 mi (8,566.16 km) |
| Difficult Run to Sogutlu | 5,295.38 mi (8,522.08 km) |
| Difficult Run to Soke | 5,308.89 mi (8,543.84 km) |
| Difficult Run to Solhan | 5,793.44 mi (9,323.64 km) |
| Difficult Run to Soma | 5,254.29 mi (8,455.96 km) |
| Difficult Run to Sorgun | 5,530.14 mi (8,899.90 km) |
