| Difficult Run to Cosham | 3,653.63 mi (5,879.96 km) |
| Difficult Run to Costessey | 3,706.06 mi (5,964.33 km) |
| Difficult Run to Cottingham | 3,618.21 mi (5,822.95 km) |
| Difficult Run to Coulsdon | 3,681.20 mi (5,924.31 km) |
| Difficult Run to Coventry | 3,602.37 mi (5,797.46 km) |
| Difficult Run to Cowdenbeath | 3,464.27 mi (5,575.20 km) |
| Difficult Run to Cowes | 3,645.75 mi (5,867.27 km) |
| Difficult Run to Cowley | 3,662.66 mi (5,894.48 km) |
| Difficult Run to Cowley | 3,628.33 mi (5,839.24 km) |
| Difficult Run to Cramlington | 3,548.30 mi (5,710.44 km) |
| Difficult Run to Cranleigh | 3,671.37 mi (5,908.50 km) |
| Difficult Run to Crawley | 3,683.93 mi (5,928.72 km) |
| Difficult Run to Crayford | 3,691.39 mi (5,940.73 km) |
| Difficult Run to Crewe | 3,551.52 mi (5,715.63 km) |
| Difficult Run to Crigglestone | 3,577.44 mi (5,757.34 km) |
