| Difficult Run to Cromer | 3,703.49 mi (5,960.18 km) |
| Difficult Run to Crosby | 3,520.67 mi (5,665.96 km) |
| Difficult Run to Crowborough | 3,699.29 mi (5,953.43 km) |
| Difficult Run to Croxley Green | 3,661.53 mi (5,892.67 km) |
| Difficult Run to Croydon | 3,681.22 mi (5,924.36 km) |
| Difficult Run to Cudworth | 3,582.95 mi (5,766.20 km) |
| Difficult Run to Culcheth | 3,541.64 mi (5,699.71 km) |
| Difficult Run to Cullercoats | 3,554.99 mi (5,721.21 km) |
| Difficult Run to Cumbernauld | 3,442.55 mi (5,540.24 km) |
| Difficult Run to Cumnock | 3,439.79 mi (5,535.81 km) |
| Difficult Run to Cupar | 3,473.74 mi (5,590.44 km) |
| Difficult Run to Cwmbran | 3,556.10 mi (5,722.99 km) |
| Difficult Run to Dagenham | 3,687.79 mi (5,934.92 km) |
| Difficult Run to Dalkeith | 3,478.61 mi (5,598.28 km) |
| Difficult Run to Darfield | 3,585.06 mi (5,769.60 km) |
