| Difficult Run to Droylsden | 3,555.45 mi (5,721.94 km) |
| Difficult Run to Dudley | 3,577.06 mi (5,756.73 km) |
| Difficult Run to Dukinfield | 3,558.60 mi (5,727.01 km) |
| Difficult Run to Dumbarton | 3,420.83 mi (5,505.30 km) |
| Difficult Run to Dumfries | 3,471.17 mi (5,586.31 km) |
| Difficult Run to Dunbar | 3,497.25 mi (5,628.29 km) |
| Difficult Run to Dunblane | 3,439.97 mi (5,536.09 km) |
| Difficult Run to Dundee | 3,473.00 mi (5,589.25 km) |
| Difficult Run to Dunfermline | 3,461.50 mi (5,570.75 km) |
| Difficult Run to Dunstable | 3,653.28 mi (5,879.38 km) |
| Difficult Run to Durham | 3,554.27 mi (5,720.05 km) |
| Difficult Run to Ealing | 3,670.32 mi (5,906.80 km) |
| Difficult Run to Earlestown | 3,536.59 mi (5,691.59 km) |
| Difficult Run to Earley | 3,646.25 mi (5,868.08 km) |
| Difficult Run to East Barnet | 3,673.09 mi (5,911.27 km) |
