| Difficult Run to Southwater | 3,679.04 mi (5,920.85 km) |
| Difficult Run to Southwick | 3,558.08 mi (5,726.18 km) |
| Difficult Run to Southwick | 3,687.94 mi (5,935.16 km) |
| Difficult Run to Sowerby Bridge | 3,560.94 mi (5,730.79 km) |
| Difficult Run to Spalding | 3,648.93 mi (5,872.39 km) |
| Difficult Run to Spennymoor | 3,555.02 mi (5,721.25 km) |
| Difficult Run to Spitalfields | 3,679.46 mi (5,921.51 km) |
| Difficult Run to Spondon | 3,596.45 mi (5,787.93 km) |
| Difficult Run to Stafford | 3,570.06 mi (5,745.46 km) |
| Difficult Run to Staines-upon-Thames | 3,663.49 mi (5,895.81 km) |
| Difficult Run to Stalybridge | 3,560.11 mi (5,729.44 km) |
| Difficult Run to Stamford | 3,638.45 mi (5,855.52 km) |
| Difficult Run to Standish | 3,533.52 mi (5,686.65 km) |
| Difficult Run to Stanford le Hope | 3,699.84 mi (5,954.31 km) |
| Difficult Run to Stanley | 3,577.92 mi (5,758.10 km) |
