| Difficult Run to Sudbury | 3,700.31 mi (5,955.07 km) |
| Difficult Run to Sunbury | 3,667.28 mi (5,901.92 km) |
| Difficult Run to Sunderland | 3,559.29 mi (5,728.12 km) |
| Difficult Run to Sunninghill | 3,658.29 mi (5,887.44 km) |
| Difficult Run to Surbiton | 3,672.70 mi (5,910.64 km) |
| Difficult Run to Sutton | 3,677.85 mi (5,918.93 km) |
| Difficult Run to Sutton Coldfield | 3,586.72 mi (5,772.27 km) |
| Difficult Run to Sutton in Ashfield | 3,597.94 mi (5,790.32 km) |
| Difficult Run to Sutton on Hull | 3,622.50 mi (5,829.85 km) |
| Difficult Run to Swadlincote | 3,593.14 mi (5,782.59 km) |
| Difficult Run to Swallownest | 3,590.71 mi (5,778.69 km) |
| Difficult Run to Swanage | 3,621.61 mi (5,828.42 km) |
| Difficult Run to Swindon | 3,608.88 mi (5,807.94 km) |
| Difficult Run to Swinton | 3,588.65 mi (5,775.38 km) |
| Difficult Run to Swinton | 3,547.65 mi (5,709.40 km) |
