| Difficult Run to Twickenham | 3,670.26 mi (5,906.72 km) |
| Difficult Run to Tyldesley | 3,542.61 mi (5,701.28 km) |
| Difficult Run to Tynemouth | 3,555.66 mi (5,722.29 km) |
| Difficult Run to Uckfield | 3,698.86 mi (5,952.75 km) |
| Difficult Run to Ulverston | 3,505.87 mi (5,642.16 km) |
| Difficult Run to Upminster | 3,691.86 mi (5,941.48 km) |
| Difficult Run to Upton | 3,519.96 mi (5,664.83 km) |
| Difficult Run to Urmston | 3,547.52 mi (5,709.18 km) |
| Difficult Run to Usworth | 3,552.20 mi (5,716.71 km) |
| Difficult Run to Uttoxeter | 3,578.56 mi (5,759.14 km) |
| Difficult Run to Uxbridge | 3,662.52 mi (5,894.25 km) |
| Difficult Run to Verwood | 3,619.14 mi (5,824.44 km) |
| Difficult Run to Wakefield | 3,578.03 mi (5,758.29 km) |
| Difficult Run to Walkden | 3,545.15 mi (5,705.36 km) |
| Difficult Run to Wallasey | 3,522.40 mi (5,668.76 km) |
