| Drexel Hill to Southern Pines (North Carolina) | 397.93 mi (640.40 km) |
| Drexel Hill to Southfield (Michigan) | 448.67 mi (722.07 km) |
| Drexel Hill to Southgate (Michigan) | 439.86 mi (707.89 km) |
| Drexel Hill to Southlake (Texas) | 1,302.50 mi (2,096.17 km) |
| Drexel Hill to Spanaway (Washington) | 2,374.27 mi (3,821.02 km) |
| Drexel Hill to Spanish Fork (Utah) | 1,908.82 mi (3,071.95 km) |
| Drexel Hill to Spanish Lake (Missouri) | 799.17 mi (1,286.14 km) |
| Drexel Hill to Spanish Springs (Nevada) | 2,330.14 mi (3,749.99 km) |
| Drexel Hill to Sparks (Nevada) | 2,334.04 mi (3,756.27 km) |
| Drexel Hill to Spartanburg (South Carolina) | 501.23 mi (806.66 km) |
| Drexel Hill to Spearfish (South Dakota) | 1,484.23 mi (2,388.64 km) |
| Drexel Hill to Speedway (Indiana) | 580.09 mi (933.56 km) |
| Drexel Hill to Spencer (Iowa) | 1,047.25 mi (1,685.39 km) |
| Drexel Hill to Spokane (Washington) | 2,138.90 mi (3,442.22 km) |
| Drexel Hill to Spokane Valley (Washington) | 2,129.67 mi (3,427.38 km) |
