| Drobeta-Turnu Severin to Sceaux | 1,002.78 mi (1,613.82 km) |
| Drobeta-Turnu Severin to Schiltigheim | 756.97 mi (1,218.23 km) |
| Drobeta-Turnu Severin to Scionzier | 786.62 mi (1,265.95 km) |
| Drobeta-Turnu Severin to Seclin | 997.53 mi (1,605.36 km) |
| Drobeta-Turnu Severin to Sedan | 899.82 mi (1,448.13 km) |
| Drobeta-Turnu Severin to Selestat | 764.04 mi (1,229.61 km) |
| Drobeta-Turnu Severin to Sene | 1,227.37 mi (1,975.27 km) |
| Drobeta-Turnu Severin to Senlis | 994.65 mi (1,600.74 km) |
| Drobeta-Turnu Severin to Sens | 951.77 mi (1,531.73 km) |
| Drobeta-Turnu Severin to Septemes-les-Vallons | 861.42 mi (1,386.32 km) |
| Drobeta-Turnu Severin to Serris | 981.41 mi (1,579.43 km) |
| Drobeta-Turnu Severin to Sete | 943.33 mi (1,518.15 km) |
| Drobeta-Turnu Severin to Sevran | 993.63 mi (1,599.09 km) |
| Drobeta-Turnu Severin to Sevres | 1,006.81 mi (1,620.31 km) |
| Drobeta-Turnu Severin to Seynod | 808.26 mi (1,300.76 km) |
