| Drobeta-Turnu Severin to Santa Venerina | 618.69 mi (995.68 km) |
| Drobeta-Turnu Severin to Santeramo in Colle | 398.99 mi (642.11 km) |
| Drobeta-Turnu Severin to Santo Stefano di Magra | 628.88 mi (1,012.09 km) |
| Drobeta-Turnu Severin to Santo Stino di Livenza | 490.96 mi (790.12 km) |
| Drobeta-Turnu Severin to Sarezzo | 610.18 mi (981.99 km) |
| Drobeta-Turnu Severin to Sarno | 485.23 mi (780.91 km) |
| Drobeta-Turnu Severin to Saronno | 666.29 mi (1,072.30 km) |
| Drobeta-Turnu Severin to Sarzana | 627.12 mi (1,009.26 km) |
| Drobeta-Turnu Severin to Sassari | 763.69 mi (1,229.05 km) |
| Drobeta-Turnu Severin to Sasso Marconi | 561.41 mi (903.51 km) |
| Drobeta-Turnu Severin to Sassuolo | 583.27 mi (938.68 km) |
| Drobeta-Turnu Severin to Sava | 390.42 mi (628.33 km) |
| Drobeta-Turnu Severin to Saviano | 485.54 mi (781.40 km) |
| Drobeta-Turnu Severin to Savigliano | 737.19 mi (1,186.39 km) |
| Drobeta-Turnu Severin to Savignano sul Panaro | 571.52 mi (919.77 km) |
