| Drobeta-Turnu Severin to Sesimbra | 1,685.09 mi (2,711.89 km) |
| Drobeta-Turnu Severin to Setubal | 1,672.59 mi (2,691.77 km) |
| Drobeta-Turnu Severin to Sever do Vouga | 1,588.35 mi (2,556.20 km) |
| Drobeta-Turnu Severin to Silves | 1,691.10 mi (2,721.56 km) |
| Drobeta-Turnu Severin to Sines | 1,688.06 mi (2,716.67 km) |
| Drobeta-Turnu Severin to Sintra | 1,689.05 mi (2,718.27 km) |
| Drobeta-Turnu Severin to Sobrado de Paiva | 1,576.42 mi (2,537.00 km) |
| Drobeta-Turnu Severin to Sobral de Monte Agraco | 1,671.30 mi (2,689.70 km) |
| Drobeta-Turnu Severin to Soure | 1,618.29 mi (2,604.38 km) |
| Drobeta-Turnu Severin to Tabua | 1,580.80 mi (2,544.05 km) |
| Drobeta-Turnu Severin to Tavira | 1,654.87 mi (2,663.26 km) |
| Drobeta-Turnu Severin to Tomar | 1,619.34 mi (2,606.07 km) |
| Drobeta-Turnu Severin to Tondela | 1,579.63 mi (2,542.16 km) |
| Drobeta-Turnu Severin to Torre de Moncorvo | 1,516.92 mi (2,441.24 km) |
| Drobeta-Turnu Severin to Torres Novas | 1,628.63 mi (2,621.02 km) |
