| Dumfries to Sestu | 1,237.65 mi (1,991.80 km) |
| Dumfries to Settimo Torinese | 849.35 mi (1,366.90 km) |
| Dumfries to Seveso | 857.34 mi (1,379.76 km) |
| Dumfries to Sezze | 1,204.58 mi (1,938.59 km) |
| Dumfries to Siano | 1,291.66 mi (2,078.72 km) |
| Dumfries to Siena | 1,050.95 mi (1,691.34 km) |
| Dumfries to Signa | 1,017.91 mi (1,638.17 km) |
| Dumfries to Silea | 952.11 mi (1,532.27 km) |
| Dumfries to Silvi Paese | 1,175.89 mi (1,892.41 km) |
| Dumfries to Sinalunga | 1,068.17 mi (1,719.05 km) |
| Dumfries to Siniscola | 1,171.90 mi (1,885.99 km) |
| Dumfries to Sinnai | 1,239.89 mi (1,995.41 km) |
| Dumfries to Siracusa | 1,527.84 mi (2,458.82 km) |
| Dumfries to Solaro | 857.42 mi (1,379.88 km) |
| Dumfries to Soliera | 959.33 mi (1,543.88 km) |
