| Eastbourne to Sacile | 650.55 mi (1,046.96 km) |
| Eastbourne to Sala Consilina | 1,026.79 mi (1,652.45 km) |
| Eastbourne to Salemi | 1,085.04 mi (1,746.21 km) |
| Eastbourne to Salerno | 983.45 mi (1,582.70 km) |
| Eastbourne to Salo | 591.31 mi (951.62 km) |
| Eastbourne to Salsomaggiore Terme | 609.02 mi (980.12 km) |
| Eastbourne to Saluzzo | 539.34 mi (867.99 km) |
| Eastbourne to Salzano | 653.49 mi (1,051.70 km) |
| Eastbourne to Samarate | 528.70 mi (850.86 km) |
| Eastbourne to San Benedetto del Tronto | 837.32 mi (1,347.54 km) |
| Eastbourne to San Biagio di Callalta | 657.26 mi (1,057.76 km) |
| Eastbourne to San Bonifacio | 627.91 mi (1,010.52 km) |
| Eastbourne to San Casciano in Val di Pesa | 708.22 mi (1,139.77 km) |
| Eastbourne to San Cataldo | 1,138.26 mi (1,831.86 km) |
| Eastbourne to San Cesareo | 857.96 mi (1,380.75 km) |
