| Eastbourne to Sestu | 900.32 mi (1,448.92 km) |
| Eastbourne to Settimo Torinese | 520.73 mi (838.03 km) |
| Eastbourne to Seveso | 539.54 mi (868.30 km) |
| Eastbourne to Sezze | 883.60 mi (1,422.02 km) |
| Eastbourne to Siano | 974.80 mi (1,568.79 km) |
| Eastbourne to Siena | 730.53 mi (1,175.67 km) |
| Eastbourne to Signa | 698.88 mi (1,124.75 km) |
| Eastbourne to Silea | 655.31 mi (1,054.62 km) |
| Eastbourne to Silvi Paese | 865.30 mi (1,392.57 km) |
| Eastbourne to Sinalunga | 749.21 mi (1,205.73 km) |
| Eastbourne to Siniscola | 836.92 mi (1,346.89 km) |
| Eastbourne to Sinnai | 902.69 mi (1,452.74 km) |
| Eastbourne to Siracusa | 1,200.98 mi (1,932.79 km) |
| Eastbourne to Solaro | 539.06 mi (867.54 km) |
| Eastbourne to Soliera | 645.56 mi (1,038.93 km) |
