| Eastbourne to Spello | 792.79 mi (1,275.88 km) |
| Eastbourne to Spilamberto | 658.69 mi (1,060.06 km) |
| Eastbourne to Spilimbergo | 659.49 mi (1,061.35 km) |
| Eastbourne to Spinea | 656.88 mi (1,057.14 km) |
| Eastbourne to Spoleto | 805.06 mi (1,295.62 km) |
| Eastbourne to Spoltore | 870.84 mi (1,401.48 km) |
| Eastbourne to Spresiano | 648.20 mi (1,043.17 km) |
| Eastbourne to Squinzano | 1,112.06 mi (1,789.69 km) |
| Eastbourne to Statte | 1,074.52 mi (1,729.28 km) |
| Eastbourne to Stezzano | 557.25 mi (896.81 km) |
| Eastbourne to Strada | 716.39 mi (1,152.92 km) |
| Eastbourne to Stradella | 572.63 mi (921.56 km) |
| Eastbourne to Striano | 969.75 mi (1,560.66 km) |
| Eastbourne to Subiaco | 861.73 mi (1,386.81 km) |
| Eastbourne to Sulmona | 883.87 mi (1,422.46 km) |
