| Eastpointe to Sacile | 4,429.22 mi (7,128.14 km) |
| Eastpointe to Sala Consilina | 4,785.54 mi (7,701.58 km) |
| Eastpointe to Salemi | 4,779.11 mi (7,691.24 km) |
| Eastpointe to Salerno | 4,738.94 mi (7,626.59 km) |
| Eastpointe to Salo | 4,365.92 mi (7,026.28 km) |
| Eastpointe to Salsomaggiore Terme | 4,374.37 mi (7,039.87 km) |
| Eastpointe to Saluzzo | 4,279.45 mi (6,887.11 km) |
| Eastpointe to Salzano | 4,431.42 mi (7,131.69 km) |
| Eastpointe to Samarate | 4,295.12 mi (6,912.33 km) |
| Eastpointe to San Benedetto del Tronto | 4,607.37 mi (7,414.85 km) |
| Eastpointe to San Biagio di Callalta | 4,435.75 mi (7,138.64 km) |
| Eastpointe to San Bonifacio | 4,403.66 mi (7,087.01 km) |
| Eastpointe to San Casciano in Val di Pesa | 4,469.16 mi (7,192.42 km) |
| Eastpointe to San Cataldo | 4,844.09 mi (7,795.81 km) |
| Eastpointe to San Cesareo | 4,610.40 mi (7,419.72 km) |
