| Eastpointe to Ede | 3,944.31 mi (6,347.75 km) |
| Eastpointe to Eemnes | 3,922.20 mi (6,312.17 km) |
| Eastpointe to Eerbeek | 3,957.26 mi (6,368.59 km) |
| Eastpointe to Eersel | 3,954.33 mi (6,363.88 km) |
| Eastpointe to Eijsden | 3,988.37 mi (6,418.67 km) |
| Eastpointe to Eindhoven | 3,957.86 mi (6,369.56 km) |
| Eastpointe to Elburg | 3,937.94 mi (6,337.51 km) |
| Eastpointe to Emmeloord | 3,925.76 mi (6,317.91 km) |
| Eastpointe to Emmen | 3,965.56 mi (6,381.95 km) |
| Eastpointe to Enkhuizen | 3,909.43 mi (6,291.62 km) |
| Eastpointe to Enschede | 3,984.56 mi (6,412.52 km) |
| Eastpointe to Epe | 3,946.18 mi (6,350.76 km) |
| Eastpointe to Ermelo | 3,934.22 mi (6,331.51 km) |
| Eastpointe to Etten-Leur | 3,921.33 mi (6,310.78 km) |
| Eastpointe to Franeker | 3,901.86 mi (6,279.44 km) |
