| Edessa to Enumclaw (Washington) | 5,968.24 mi (9,604.96 km) |
| Edessa to Ephrata (Pennsylvania) | 4,850.13 mi (7,805.54 km) |
| Edessa to Erie (Colorado) | 5,937.66 mi (9,555.74 km) |
| Edessa to Erie (Pennsylvania) | 4,927.73 mi (7,930.42 km) |
| Edessa to Erlanger (Kentucky) | 5,247.07 mi (8,444.35 km) |
| Edessa to Escanaba (Michigan) | 5,033.64 mi (8,100.86 km) |
| Edessa to Escondido (California) | 6,703.08 mi (10,787.57 km) |
| Edessa to Española (New Mexico) | 6,194.29 mi (9,968.74 km) |
| Edessa to Essex (Maryland) | 4,898.16 mi (7,882.82 km) |
| Edessa to Essex Junction (Vermont) | 4,549.03 mi (7,320.96 km) |
| Edessa to Estelle (Louisiana) | 5,910.92 mi (9,512.70 km) |
| Edessa to Estero (Florida) | 5,707.89 mi (9,185.97 km) |
| Edessa to Euclid (Ohio) | 5,008.41 mi (8,060.26 km) |
| Edessa to Eufaula (Alabama) | 5,600.84 mi (9,013.69 km) |
| Edessa to Eugene (Oregon) | 6,187.43 mi (9,957.70 km) |
