| Edinburgh to Sestu | 1,280.53 mi (2,060.81 km) |
| Edinburgh to Settimo Torinese | 886.65 mi (1,426.92 km) |
| Edinburgh to Seveso | 890.07 mi (1,432.43 km) |
| Edinburgh to Sezze | 1,236.86 mi (1,990.53 km) |
| Edinburgh to Siano | 1,321.92 mi (2,127.42 km) |
| Edinburgh to Siena | 1,083.59 mi (1,743.87 km) |
| Edinburgh to Signa | 1,050.15 mi (1,690.05 km) |
| Edinburgh to Silea | 977.29 mi (1,572.80 km) |
| Edinburgh to Silvi Paese | 1,204.20 mi (1,937.97 km) |
| Edinburgh to Sinalunga | 1,100.14 mi (1,770.50 km) |
| Edinburgh to Siniscola | 1,212.20 mi (1,950.85 km) |
| Edinburgh to Sinnai | 1,282.56 mi (2,064.08 km) |
| Edinburgh to Siracusa | 1,562.15 mi (2,514.04 km) |
| Edinburgh to Solaro | 890.35 mi (1,432.87 km) |
| Edinburgh to Soliera | 989.91 mi (1,593.10 km) |
