| Edwardsville to Cortona | 4,963.45 mi (7,987.90 km) |
| Edwardsville to Cosenza | 5,307.14 mi (8,541.02 km) |
| Edwardsville to Cossato | 4,718.13 mi (7,593.10 km) |
| Edwardsville to Costa Volpino | 4,784.84 mi (7,700.45 km) |
| Edwardsville to Creazzo | 4,851.24 mi (7,807.31 km) |
| Edwardsville to Crema | 4,786.63 mi (7,703.33 km) |
| Edwardsville to Cremona | 4,809.82 mi (7,740.65 km) |
| Edwardsville to Crevalcore | 4,871.02 mi (7,839.15 km) |
| Edwardsville to Crispiano | 5,289.46 mi (8,512.56 km) |
| Edwardsville to Crosia | 5,316.48 mi (8,556.05 km) |
| Edwardsville to Crotone | 5,352.31 mi (8,613.72 km) |
| Edwardsville to Cuneo | 4,738.69 mi (7,626.18 km) |
| Edwardsville to Cuorgne | 4,704.10 mi (7,570.52 km) |
| Edwardsville to Cusano Milanino | 4,759.49 mi (7,659.66 km) |
| Edwardsville to Cutro | 5,349.07 mi (8,608.49 km) |
