| Edwardsville to Nymburk | 4,795.17 mi (7,717.08 km) |
| Edwardsville to Olomouc | 4,898.21 mi (7,882.91 km) |
| Edwardsville to Opava | 4,906.44 mi (7,896.15 km) |
| Edwardsville to Orlova | 4,928.75 mi (7,932.06 km) |
| Edwardsville to Ostrava | 4,924.37 mi (7,925.01 km) |
| Edwardsville to Ostrov | 4,714.98 mi (7,588.02 km) |
| Edwardsville to Otrokovice | 4,924.50 mi (7,925.22 km) |
| Edwardsville to Pardubice | 4,827.46 mi (7,769.04 km) |
| Edwardsville to Pelhrimov | 4,832.79 mi (7,777.62 km) |
| Edwardsville to Pisek | 4,798.91 mi (7,723.10 km) |
| Edwardsville to Plzen | 4,753.17 mi (7,649.49 km) |
| Edwardsville to Podebrady | 4,799.71 mi (7,724.39 km) |
| Edwardsville to Policka | 4,858.23 mi (7,818.57 km) |
| Edwardsville to Prachatice | 4,805.51 mi (7,733.72 km) |
| Edwardsville to Prague | 4,777.06 mi (7,687.94 km) |
