| El Puerto de Santa Maria to Santa Venerina | 1,175.74 mi (1,892.17 km) |
| El Puerto de Santa Maria to Santeramo in Colle | 1,268.86 mi (2,042.03 km) |
| El Puerto de Santa Maria to Santo Stefano di Magra | 994.27 mi (1,600.13 km) |
| El Puerto de Santa Maria to Santo Stino di Livenza | 1,163.64 mi (1,872.69 km) |
| El Puerto de Santa Maria to Sarezzo | 1,055.40 mi (1,698.51 km) |
| El Puerto de Santa Maria to Sarno | 1,157.35 mi (1,862.57 km) |
| El Puerto de Santa Maria to Saronno | 1,006.72 mi (1,620.16 km) |
| El Puerto de Santa Maria to Sarzana | 994.79 mi (1,600.96 km) |
| El Puerto de Santa Maria to Sassari | 845.33 mi (1,360.43 km) |
| El Puerto de Santa Maria to Sasso Marconi | 1,060.98 mi (1,707.48 km) |
| El Puerto de Santa Maria to Sassuolo | 1,044.71 mi (1,681.30 km) |
| El Puerto de Santa Maria to Sava | 1,308.36 mi (2,105.60 km) |
| El Puerto de Santa Maria to Saviano | 1,153.14 mi (1,855.80 km) |
| El Puerto de Santa Maria to Savigliano | 912.69 mi (1,468.83 km) |
| El Puerto de Santa Maria to Savignano sul Panaro | 1,053.69 mi (1,695.75 km) |
